Open AccessPeripheral microcircuiation in patients over 60 years with atherosclerosis of lower limb arteries
Author(s) -
О. В. Каменская,
А. С. Клинкова,
А. А. Карпенко,
А. М. Караськов,
Vladimir Starodubtsev,
Г. А. Зейдлиц
Publication year - 2015
Publication title -
patologiâ krovoobraŝeniâ i kardiohirurgiâ/patologiâ krovoobrašeniâ i kardiohirurgiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.136
H-Index - 3
eISSN - 2500-3119
pISSN - 1681-3472
DOI - 10.21688/1681-3472-2013-3-22-26
Subject(s) - peripheral , medicine , microcirculation , cardiology , orthostatic vital signs , revascularization , laser doppler velocimetry , ischemia , blood flow , critical limb ischemia , blood pressure , myocardial infarction
We investigated peripheral microcirculatory blood flow (MBF) by using laser Doppler flowmetry in 146 patients with IIB-IV stage chronic ischemia of lower limbs (CILL) according to the Pokrovsky-Fontaine classification. The objective was to study the state of peripheral MBF while carrying out functional tests in patients over 60 years with IIB-IV stage CILL before and after revascularization of lower limb arteries. When ageing, CILL patients demonstrate a decrease in the peripheral MBF baseline indicators and an increase in the quantity of defects of regulatory mechanisms and functional reserves of microcirculation, which manifest themselves as a severe paradoxical reaction of the microvasculature during an orthostatic test. In the early postoperative period the elderly patients tend to have reduced functional reserves and regulation mechanisms of MBF, with a high volume and degree of severity of MBF paradoxical reactions during an orthostatic test.