Open AccessTreatment of rare bleeding disorders
Author(s) -
Д. Б. Флоринский,
П. А. Жарков
Publication year - 2021
Publication title -
rossijskij žurnal detskoj gematologii i onkologii
Language(s) - English
Resource type - Journals
eISSN - 2413-5496
pISSN - 2311-1267
DOI - 10.21682/2311-1267-2020-7-4-71-76
Subject(s) - medicine , coagulation , coagulation disorder , vitamin k , clotting factor , afibrinogenemia , gastroenterology , fibrinogen , intensive care medicine , surgery
Rare bleeding disorders include inherited deficiencies of fibrinogen, factors (F)II, FV, FVII, FX, FXI, FXII, and FV + FVIII, as well as a multiple deficiency of vitamin K-dependent coagulation factors. Some of these deficiencies are more studied, due to the large number of patients, some are extremely rare, and so at this stage it is quite difficult for them to develop a universal approach to therapy and prophylactic treatment. The purpose of this review was to evaluate treatment options for these deficiencies.