Open AccessMelanotic neuroectodermal tumor of infancy: a description of the experience of Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology and literature review
Author(s) -
А. М. Сулейманова,
С. С. Озеров,
В. Ю. Рощин,
Н. С. Грачёв,
N. A. Bolshakov,
Alexander Druy,
Г. В. Терещенко,
Д. М. Коновалов,
Г. Б. Сагоян,
Т. В. Шаманская,
Д. Ю. Качанов,
С. Р. Варфоломеева
Publication year - 2019
Publication title -
rossijskij žurnal detskoj gematologii i onkologii
Language(s) - English
Resource type - Journals
eISSN - 2413-5496
pISSN - 2311-1267
DOI - 10.21682/2311-1267-2019-6-3-44-53
Subject(s) - medicine , radiation therapy , hematology , chemotherapy , head and neck , primitive neuroectodermal tumor , oncology , radiology , surgery
Melanotic neuroectodermal tumor of infancy (MNTI) is a rare type of tumor with uncertain clinical behavior. The tumor commonly occurred in the head and neck region. Radical surgical resection is the standard of treatment, which is often associated with high risks of severe postoperative complications due to tumor localization. Alternative methods of treatment including chemotherapy/radiotherapy are used in metastatic, locally advanced and relapsed cases of MNTI. The aim of this study was to analyze clinical and morphological characteristics of the tumor, evaluate the effectiveness of various treatment options, and to describe two clinical cases of MNTI.