Open AccessFibrinogen Degradation Products and Coagulation Parameters in Women Taking Oral Contraceptives
Author(s) -
Ghazanfar Ali Sirhindi,
Muhammad Tayyib,
Tahira Tasneem,
Muhammad Farooq,
Nasir Ahmad Chaudhary
Publication year - 2016
Publication title -
annals of king edward medical university
Language(s) - English
Resource type - Journals
eISSN - 2079-7192
pISSN - 2079-0694
DOI - 10.21649/akemu.v9i3.1331
Subject(s) - medicine , partial thromboplastin time , fibrinogen , coagulation , prothrombin time , thrombin time , coagulation testing , combined oral contraceptives , endocrinology , gynecology , population , family planning , research methodology , environmental health
A study plan was designed to estimate the coagulation parameters like Prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen level and fibrinogen degradation products (FDPs). In this study, coagulation parameters were compared in combined oral contraceptives (COCs) and control group. 40 subjects of COCs with 20 normal females without hormonal contraceptive were included in this study. Blood samples were collected for special coagulation parameters. FDPs were significantly elevated in subjects using COCs as compared to normal control. PT and APTT were shortened in COCs. Fibrinogen levels were increased significantly in COCs when compared with control groups.