Open AccessPresence of Left Ventricular Diastolic Dysfunction in Patients of Chronic Obstructive Pulmonary Disease
Author(s) -
Kaleem Ullah,
Zafar Niaz,
Sami Ullah Mumtaz,
Sajid Abaidullah
Publication year - 2018
Publication title -
annals of king edward medical university
Language(s) - English
Resource type - Journals
eISSN - 2079-7192
pISSN - 2079-0694
DOI - 10.21649/akemu.v24i1.2306
Subject(s) - medicine , cardiology , copd , diastole , ejection fraction , pulmonary artery , coronary artery disease , heart failure , blood pressure
The relationship between chronic obstructive pulmonary disease (COPD) and cardiovascular diseases strongly exists as diastolic dysfunction is commonly reported in COPD patients. Objective: This study was conducted to determine the presence of left ventricular diastolic dysfunction in patients of COPD. Material and Methods: A cross sectional study was conducted in Mayo Hospital Lahore for one year. A total of 50 confirmed cases of COPD were included in the study. History of smoking was taken and subjects were examined for positive signs for the clinical, ECG, x-ray chest PA view and pulmonary function tests. Additionally, they were subjected to echocardiography and left ventricular diastolic dysfunctions were noted. Results: In our study, mean age of the patients was 60.7±6.2 years and mean FEV1/FVC ratio was 56.9±14.3%. Similarly mean ejection fraction of the patients turned out to be 60.6±4.6. The mean peak mitral filling velocity of the patients was 69.8±15.9 cm/s. The mean peak mitral filling rate of the patients was 57.2±30.9 cm/s and mean E/A ratio was 1.3±0.3. The mean iso-volumetric relaxation time of the patients was 84.2±14.7 msec. The mean mitral E deceleration time of the patients was 187.4±25.1 msec. The mean atrial flow reversal was 0.28±0.04. There were 14 (28%) patients having left ventricular diastolic dysfunction. Conclusion: COPD patients had left ventricular diastolic dysfunction and it was related to increase in pulmonary artery pressure.