Open AccessRole of antibiotic prophylaxis in clean and clean contaminated elective surgery
Author(s) -
Muhammad Waris Farooka,
Wasim Hayat Khan,
H. Parvez,
Mahmood Ayyaz
Publication year - 2016
Publication title -
annals of king edward medical university
Language(s) - English
Resource type - Journals
eISSN - 2079-7192
pISSN - 2079-0694
DOI - 10.21649/akemu.v11i4.1128
Subject(s) - medicine , cefuroxime , antibiotic prophylaxis , placebo , antibiotics , surgery , randomized controlled trial , single center , alternative medicine , pathology , microbiology and biotechnology , biology
Antibiotic prophylaxis is a recognized concept in surgery. We studied the need for prophylaxis in clean and clean contaminated surgery in the setting of third world tertiary care center. A randomized single blind study was conducted with three arms. 278 patients of ASA and 2 were included in this study. They were randomized to prophylaxis with Cefuroxime, triple regime and placebo. The placebo wing was terminated prematurely due to unacceptable infection rate and Cefuroxime was found to be equal or better than triple regime in our study.