Open AccessXeroderma Pigmentosum
Author(s) -
Muhammad Ahmad Ghazi,
Amna Maqsood,
Yasir Akram,
Muhammad Arshad Cheema
Publication year - 2016
Publication title -
annals of king edward medical university
Language(s) - English
Resource type - Journals
eISSN - 2079-7192
pISSN - 2079-0694
DOI - 10.21649/akemu.v11i4.1122
Subject(s) - xeroderma pigmentosum , medicine , dermatology , melanoma , cancer research , dna , dna repair , genetics , biology
Xeroderma pigmentosum comprises of a heterogeneous group of autosomal recessive hereditary diseases, which are characterized by a number of clinical characteristics and abnormal DNA repair mechanism. These patients are prone to multiple cutaneous malignancies at an early stage in life. We present 2 cases of xeoderma pigmentosum with malignant melanoma and conclude that such cases must be identified at an early stage and properly educated to protect themselves from malignancies.