Open AccessNon surgical treatment of chronic anal fissure: one year`s experience with GTN paste
Author(s) -
Rizwan Aziz,
Faridud Din,
Muhammad Shoaib,
Muhammad Kamran
Publication year - 2016
Publication title -
annals of king edward medical university
Language(s) - English
Resource type - Journals
eISSN - 2079-7192
pISSN - 2079-0694
DOI - 10.21649/akemu.v11i4.1063
Subject(s) - medicine , anal fissure , surgery , headaches , anesthesia
Objective: Assessment of the efficacy of topical 0.2% glyceryl trinitrate (GTN) paste in the treatment of chronic anal fissure. Patients and Methods: Sixty two patients were treated with 0.2% GTN paste and reviewed at 3, 6 and 12 weeks interval to assess efficacy and side effects. Results: At 6 weeks, 72% of patients were treated successfully. In 28% of cases treatment was unsuccessful. At 12weeks follow up there was no early recurrence. The prevalence of headaches was 70%. Conclusions: The use of GTN induces rapid healing of chronic anal fissures with a 72% healing rate in this study. But balance is required between fissure healing and headache intolerance.