Open AccessComparison of Cycle Outcomes Among Women with Endometrioma or Non-Functional Cysts Versus Control
Author(s) -
Enis Özkaya,
Ebru Çöğendez,
Elif Tozkır,
Saadet Unsal,
Ahmet Yavuz,
G. Tunali,
Özgür Uzun,
Evrim Bostancı Ergen,
S Eser
Publication year - 2021
Publication title -
gynecology obstetrics and reproductive medicine
Language(s) - English
Resource type - Journals
ISSN - 2602-4918
DOI - 10.21613/gorm.2020.1110
Subject(s) - antral follicle , ovarian reserve , follicular phase , infertility , in vitro fertilisation , follicle , pregnancy rate , medicine , pregnancy , gonadotropin , ovarian follicle , gynecology , hormone , ovary , endometriosis , follicle stimulating hormone , anti müllerian hormone , cyst , biology , luteinizing hormone , surgery , genetics
OBJECTIVE: This study aimed to compare cycle outcomes among women with endometrioma or non-functional cysts versus control.STUDY DESIGN: Women under 35 years of age with unexplained infertility underwent in vitro fertilization cycle. Two hundred and ninety-nine women were included in this study. Study groups consist of women with endometrioma (n=82) or non-functional ovarian cysts (n=100) and control group (n=117). Women in each group were selected consecutively. Groups were matched for age and ovarian reserve and compared in terms of in vitro fertilization cycle outcome.RESULTS: There were no significant differences among groups in terms of mean age, early follicular phase Follicle-Stimulating Hormone, and anti-müllerian hormone levels (p>0.05). Baseline total antral follicle counts were similar among groups (p>0.05). There were significant differences among groups in terms of mean starting and total gonadotropin dose, peak estradiol level, total oocyte number, and mature oocyte numbers (p<0.05). Clinical pregnancy rates were 10.7%, 17.3%, and 31.6% in groups with non-functional cyst, endometrioma and control group respectively (p<0.05). The presence of a non-functional cystic mass of ovary on the starting day of stimulation was a risk factor for poor cycle outcome in terms of clinical pregnancy rates [OR=0.5 (95 % CI; 0.2-0.9, p=0.03)].CONCLUSION: Our data showed that the presence of any kind of cystic mass of the ovary especially the non-functional cysts on the starting day of stimulation was a risk factor for poor cycle outcomes in terms of clinical pregnancy rates.