Open AccessValorization of Hesperidin from Citrus Residues: Evaluation of Microwave-As
Author(s) -
Danielle da Silva,
João Bomfim,
Rafael Marchi,
Jéssica Amaral,
Luciano da Silva Pinto,
Rose Carlos,
Antônio G. Ferreira,
Moacir Rossi Forim,
João B. Fernandes,
Maria Fátima das Graças Fernandes da Silva,
Regiane de Tomazio de Ap. Oliveira,
David M. Buss,
William D. J. Kirk,
Toby J. A. Bruce
Publication year - 2022
Publication title -
journal of the brazilian chemical society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.337
H-Index - 70
eISSN - 1678-4790
pISSN - 0103-5053
DOI - 10.21577/0103-5053.20220050
Subject(s) - hesperidin , chemistry , flavonoid , rutin , myzus persicae , quercetin , spodoptera , yield (engineering) , food science , horticulture , nuclear chemistry , antioxidant , organic chemistry , biology , biochemistry , materials science , aphid , alternative medicine , pathology , gene , medicine , metallurgy , recombinant dna
The aim of the current study was the valorization of hesperidin, the dominant flavonoid in citrus processing waste, by microwave-assisted synthesis of hesperidin-Mg complex, improving its antioxidant activity and insecticidal potential. Here we show, for the first time, that microwaveassisted synthesis of [Mg(hesp)2(phen)]OAc (1) (hesp: hesperidin, phen: phenanthroline) improve the reaction rate and yield. The nuclear magnetic resonance (NMR) experiments proved to be powerful tools for the identification of three isomers in metal complexes. Moreover, we explore the insecticidal potential of 1 and [Mg(phen)2(Isov)]OAc (2) (Isov : isovanillic acid) complexes against three insects. Complex 1 killed 80% of adults whitefly at 0.14 μmol L-1, and 2 76% at 0.36 μmol L-1. There was a total mortality of Spodoptera frugiperda with 2 at 0.39 μmol L-1, and 83% with 1 at 0.14 μmol L-1. Both have similar activity, and represent a novel group of insecticide for Bemisia tabaci and S. frugiperda; nevertheless, the benefits of both as Myzus persicae repellent require further evaluation.