Open AccessThe use of antibiotics in newborns: effects on gastrointestinal microbiome and long-term results
Author(s) -
Yvan Vandenplas
Publication year - 2018
Publication title -
medicinskij sovet
Language(s) - English
Resource type - Journals
eISSN - 2658-5790
pISSN - 2079-701X
DOI - 10.21518/2079-701x-2018-17-163-167
Subject(s) - antibiotics , dysbiosis , irritable bowel syndrome , medicine , microbiome , gastrointestinal tract , intensive care medicine , immune system , pediatrics , immunology , gut flora , bioinformatics , biology , microbiology and biotechnology
A balanced gastrointestinal microbiome is crucial for the development of the immune system. The use of antibiotic therapy in infants often leads to intestinal dysbiosis. This article presents a convincing argument that the use of antibiotics in infants and young children affects their health in the future. The purpose of antibiotic therapy in childhood should be well thought out, because its negative effect on the gastrointestinal tract the ability to cause diarrhoea, has been proven, and, in addition, antibiotics have long-term effects: overweight, irritable bowel syndrome (IBS), allergic diseases. Conclusion: clinicians should weigh the need and consequences of using antibiotics in infancy and early childhood.