
Clinical efficacy of anti-ige-therapy in adult patients with severe uncontrolled bronchial asthma in real clinical practice
Author(s) -
Г. Л. Игнатова,
Е В Блинова,
О. Л. Минакина
Publication year - 2018
Publication title -
medicinskij sovet
Language(s) - English
Resource type - Journals
eISSN - 2658-5790
pISSN - 2079-701X
DOI - 10.21518/2079-701x-2018-15-54-58
Subject(s) - medicine , omalizumab , asthma , immunoglobulin e , incidence (geometry) , quality of life (healthcare) , clinical practice , intensive care medicine , pharmacotherapy , immunology , physical therapy , antibody , physics , nursing , optics
The article presents the results of comprehensive assessment of the efficacy of anti-IgE therapy in adult patients with severe IgE-mediated uncontrolled bronchial asthma in real clinical practice. Omalizumab added to the background anti-inflammatory therapy allowed to reduce the incidence of asthma exacerbations, achieve stable positive dynamics during severe asthma and associated allergic diseases, increase control of the disease, and improve the patients’ quality of life. The drug has a wellcharacterized long-term use safety profile.