Open AccessInflammatory factor in the clinical picture and therapy of irritable bowel syndrome
Author(s) -
В. М. Махов,
А. А. Балахонов,
М. А. Исайкина,
Yu. A. Doronina
Publication year - 2018
Publication title -
medicinskij sovet
Language(s) - English
Resource type - Journals
eISSN - 2658-5790
pISSN - 2079-701X
DOI - 10.21518/2079-701x-2018-14-67-72
Subject(s) - irritable bowel syndrome , inflammation , medicine , tumor necrosis factor alpha , inflammatory bowel diseases , histamine , drug , gastroenterology , pharmacology , inflammatory bowel disease , disease
The article shows the dynamics of evaluation of prognostic factors of irritable bowel syndrome. Evolution of the views indicates an increasing evaluation of inflammation and the role of markers of inflammation of cytokines, especially alpha-TNF in clinical manifestations. The rationale for using a complex drug based on affinity purified release-active antibodies to alpha-TNF, to the brain-specific protein S-100 and histamine-colourant is presented.