Open AccessLimbal stem cell deficiency: etiology, pathogenesis, priniciples and prospects of surgical treatment
Author(s) -
А. С. Дубовиков,
И. О. Гаврилюк,
Alexey N. Kulikov,
S.V. Churashov,
В Ф Черныш,
А. В. Безушко
Publication year - 2019
Publication title -
rossijskij oftalʹmologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2587-5760
pISSN - 2072-0076
DOI - 10.21516/2072-0076-2019-12-1-103-111
Subject(s) - pathogenesis , etiology , stem cell , medicine , transplantation , ex vivo , pathology , biology , in vivo , surgery , genetics
The review is focused on the modern view of the etiology and pathogenesis of limbal stem cells deficiency. The history of development of tissue and ex-vivo transplantation of limbal epithelial stem cells is presented. Certain promising directions of the treatment of patients with limbal stem cells deficiency are presented.