Open AccessTopic inhaled antibiotic therapy in children with prolonged adenoiditis
Author(s) -
И. М. Кириченко
Publication year - 2019
Publication title -
rossijskij vestnik perinatologii i pediatrii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.139
H-Index - 4
eISSN - 2500-2228
pISSN - 1027-4065
DOI - 10.21508/1027-4065-2019-64-3-87-90
Subject(s) - antibiotics , medicine , thiamphenicol , intensive care medicine , systemic antibiotics , antibiotic resistance , antibiotic therapy , chloramphenicol , microbiology and biotechnology , biology
Currently the issue of antibiotic resistance is urgent due to the unreasonable prescription of systemic antibiotics in the treatment of the upper respiratory tract infections. Frequent use of systemic antibiotic therapy in childhood leads to disruption of the microbiota and the development of secondary immunodeficiency. Alternative topical antibiotic therapy together with mucolytics allows the antibiotic to penetrate directly to the inflammation site and destroy biofilms. The article outlines the use of thiamphenicol glycinate acetylcysteinate in children with prolonged adenoiditis. In Russia this antibiotic is presented by Fluimucil® IT; it is manufactured in the form of a lyophilisate for both injectable solutions and solutions for inhalations and irrigation of mucous membranes. Thiamphenicol glycinate acetylcysteinate helps to improve the course of the disease, in some cases, to avoid invasive procedures and reduce the use of systemic antibiotics.