Open AccessInterferon inductors in prevention and treatment of respiratory infections in children
Author(s) -
Вахитов Хаким Муратович,
Пикуза Ольга Ивановна,
Вахитова Лилия Фаукатовна,
Закирова Альфия Мидхатовна,
Ризванова Фарида Фаритовна
Publication year - 2019
Publication title -
rossijskij vestnik perinatologii i pediatrii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.139
H-Index - 4
eISSN - 2500-2228
pISSN - 1027-4065
DOI - 10.21508/1027-4065-2019-64-3-103-108
Subject(s) - tolerability , medicine , interferon , drug , intensive care medicine , respiratory system , clinical trial , disease , immunology , pharmacology , adverse effect
In this article topical issues in treatment of acute respiratory infections in children and place of both exogenous interferons and interferon inducer drugs in their treatment are reviewed, including mechanisms of action, advantages and disadvantages of their application, special features of use in children. The latest clinical and laboratory data on the efficacy meglumine acridone acetate use in this pathology are given here. Depletion of inflammatory manifestations, correction of immune system imbalance were observed, leading to reduction of symptoms severity and disease duration, which, along with the good tolerability of the drug allows us to recommend it for widespread use in children.