Open AccessDerivatives of acridone acetic acid in pediatric practice
Author(s) -
Andrey Anatolyevich Shuldyakov,
Elena P. Lyapina,
V. K. Polyakov,
Yu. B. Barylnik,
О. Б. Лиско,
N. I. Mishagin
Publication year - 2019
Publication title -
rossijskij vestnik perinatologii i pediatrii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.139
H-Index - 4
eISSN - 2500-2228
pISSN - 1027-4065
DOI - 10.21508/1027-4065-2019-64-2-110-116
Subject(s) - medicine , rotavirus , drug , tick borne encephalitis , ribavirin , potency , encephalitis , pharmacology , immunology , virology , virus , biology , chronic hepatitis , in vitro , biochemistry
The article justifies the use of interferon inducers in a clinical practice of pediatrician. The authors isolated a group of derivatives of acridone acetic acid, which effectiveness is associated with the features of pharmacokinetics and pharmacological activity. They demonstrated preventive and therapeutic efficacy of cycloferon in the complex treatment of children with influenza and other acute respiratory viral infections, herpes virus, arbovirus, rotavirus infections, viral hepatitis and tick-borne encephalitis due to its immunomodulatory potency. The article analyzed the use of cycloferon in frequently sick children, patients with allergic diseases, chronic tonsillitis, etc.; also it showed a decrease in the frequency of relapses of both infectious and allergic diseases, the possibility of combined use with other etiotropic and symptomatic drugs.