Open AccessORGANOPHOSPHORUS COMPOUNDS CONTAINING 3-(SUBSTITUTED PHENYL)- 2-THIOXOIMIDAZOLIDIN-4-ONE AS POTENT ANTIMICROBIAL AGENTS
Author(s) -
Kalpana Chaturvedi,
AUTHOR_ID
Publication year - 2021
Publication title -
international journal of advanced research
Language(s) - English
Resource type - Journals
ISSN - 2320-5407
DOI - 10.21474/ijar01/13984
Subject(s) - antimicrobial , chemistry , proton nmr , elemental analysis , combinatorial chemistry , biological activity , carbon 13 nmr , organic chemistry , stereochemistry , biochemistry , in vitro
A series of biologically active organophosphorus compounds have been synthesized by the reactions of 4-Chlorophenyl dichlorophosphate with 3-(substitutedphenyl)-2-thioxoimidazolidin-4-one. The compounds have been characterized on the basis of elemental analyses and spectral (IR, 1H NMR 31P NMR) data. All the compounds were screened for their antimicrobial activity .They were found to possess significant anti-microbial activity.