Open AccessCLINICAL CHARACTERISTICS, LABORATORY ABNORMALITIES AND OUTCOME OF COVID-19 POSITIVE PATIENTS ADMITTED IN TERTIARY CARE HOSPITAL OF KARACHI
Author(s) -
Muhammad Farooq,
Arshad Ali,
Furquaiaz,
Nadia Shams,
Nasira Sohail,
Urooj Tabassum,
Nayyerul Islam,
Waquar Ahmed,
Uk. Consultant Peadiatrician at Wwl Nhs Trust
Publication year - 2021
Publication title -
international journal of advanced research
Language(s) - English
Resource type - Journals
ISSN - 2320-5407
DOI - 10.21474/ijar01/12920
Subject(s) - medicine , dyslipidemia , lymphocytopenia , anemia , pediatrics , diabetes mellitus , disease , lymphocyte , endocrinology
Background and Objective:COVID-19 is a corona virus disease infecting people worldwide. There are few local small-scale studies addressing this. We planned a study with good sample size to reveal clinical features and laboratory abnormalities in relation to ICU admission and mortality. Methods and Materials: This observational study was conducted at Dept. of Medicine Liyari General Hospital Karachi after ethical approval. The indoorconfirmed COVID-19 (PCR positive) patients (age>18 years) were included. Pregnant/lactating women, outdoor cases were excluded. Their demographic data, symptoms and signs,co morbidities, laboratory findings (blood complete picture, renal/liver function tests, inflammatory markers (i.e., CRP, ESR, ferritin, LDH, D dimers, troponins), area and duration of admission, disease severity, outcome as death or recovery were documented. Data was collected manually from record of the patients admitted from 15th March till 30th September 2020. The data was analyzed by SPSS software. Chi-square test applied with significant p 50 yearsage (58.9%).Frequent co morbidities were diabetes(26.1%), dyslipidemia (23%), hypertension (19.9%) and ischemic heart disease (17.3%). Fever wasmost common symptom. Tachycardia, hypotension, anemia and lymphocytopenia wereassociated with ICU admission and mortality.Inflammatory markers were elevated in most of the cases but only LDH, ferritin and D-dimers were statistically associated with ICU admission and mortality. Conclusion:This study concludes that COVID-19 positive patients with age above fifty, tachycardia, hypotension elevated LDH, Ferritin, D dimers anemia and lymphocytopenia were associated with mortality and ICU admission.