Open AccessRISPERIDONE INDUCED LEUCOPENIA AND NEUTROPENIA: A CASE REPORT AND BRIEF REVIEW OF LITERATURE
Author(s) -
M. Berghalout,
A. Ait Idar,
H. Guennouni,
K.El Ouazzani,
Imane Adali,
F. Manoudi
Publication year - 2021
Publication title -
international journal of advanced research
Language(s) - English
Resource type - Journals
ISSN - 2320-5407
DOI - 10.21474/ijar01/12505
Subject(s) - medicine , neutropenia , risperidone , clozapine , leukopenia , atypical antipsychotic , eosinophilia , thrombocytosis , eosinophil , platelet , antipsychotic , pediatrics , schizophrenia (object oriented programming) , psychiatry , toxicity , asthma
Hematological abnormalities are frequently encountered during treatment with antipsychotic drugs. Most of these are mild and of no clinical significance, but in a small minority of patients, hazardous, potentially life-threatening hematological effects, including leucopenia, neutropenia, agranulocytosis, thrombocytopenia, anaemia , leucocytosis, thrombocytosis, eosinophilia and altered platelet function. (1). Clozapine is associated with several well-known abnormalities of blood cell count (2), but some case reports associate novel antipsychotics, such as risperidone with leucopenia and agranulocytosis (3). This report describes a case of leucopenia under treatment with Oral Risperidone , suggesting the necessity of early recognition of leucopenia in order to prevent occurrence of potentially life-threatening agranulocytosis. ( 1) .