Open AccessBAKERS YEAST CATALYZED AND ULTRASOUND ACCELERATED SYNTHESIS OF 2-AMINO-2-CHROMENES
Author(s) -
Balaji S. Londhe,
Santosh L. Khillare,
Avinash M. Nalawade,
Ramrao A. Mane
Publication year - 2021
Publication title -
international journal of advanced research
Language(s) - English
Resource type - Journals
ISSN - 2320-5407
DOI - 10.21474/ijar01/12294
Subject(s) - bakers yeast , yeast , sonication , catalysis , methanol , chemistry , combinatorial chemistry , organic chemistry , saccharomyces cerevisiae , biochemistry , chromatography
In the present work, bakers yeast catalyzed efficient synthesis of 2-amino-2-chromenes in methanol is presented. Here the ultrasonication has dual role i.e. as a source of energy for the reaction and tool for the disruption of the yeast cells. The cyclocondensation has been essentially carried under neutral conditions, thus reducing the possibility of unwanted side reactions.