Open AccessSIRNA GENE THERAPY: A REVIEW
Author(s) -
Ketul Nayak,
Hiral Panchal,
Shivani Patel,
Devam Desai
Publication year - 2020
Publication title -
international journal of advanced research
Language(s) - English
Resource type - Journals
ISSN - 2320-5407
DOI - 10.21474/ijar01/11942
Subject(s) - dicer , rna interference , small interfering rna , rna silencing , genetic enhancement , gene expression , gene , trans acting sirna , gene silencing , biology , rna , computational biology , genetics
RNA inference is new concept in gene therapy it acts by expression of specific genes to treat various diseases like cancer. It is also called as RNAi. In presence of dicer enzyme long double stranded RNA (dsRNA) is cut to small interfering RNAs called SiRNAs. SiRNAs are part of RNAi. It is mainly pursued for cancer therapy. It is the new promising agent which can produce specific gene expression and also post transcriptional gene regulation process for disease treatment. In this current review I gathered lots of basic information about SiRNA like its structure, design, delivery system etc in short sweet manner.