Open AccessThe Use of Muscle Relaxants and Reversal Agents in a Setting Without Cost Restrictions: Experience from a Tertiary Academic Hospital in the Netherlands
Author(s) -
C.H. Martini,
Maarten Honing,
Lori D. Bash,
Erik Olofsen,
Marieke Niesters,
Monique van Velzen,
Albert Dahan,
Martijn Boon
Publication year - 2022
Publication title -
therapeutics and clinical risk management
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 55
eISSN - 1178-203X
pISSN - 1176-6336
DOI - 10.2147/tcrm.s350314
Subject(s) - medicine , sugammadex , rocuronium , anesthesia , neostigmine , muscle relaxant , muscle relaxation , neuromuscular monitoring , intubation , neuromuscular blocking agents , myasthenia gravis , neuromuscular blockade
Muscle relaxants are often given during general anesthesia to facilitate endotracheal intubation. However lingering effects after anesthesia-end may lead to respiratory compromise in the PACU. Strategies to reduce these adverse events include monitoring neuromuscular block, the use of short-acting agents and active pharmacological reversal before extubation. At Leiden University Medical Center (LUMC), a tertiary care academic hospital in the Netherlands, various muscle relaxants and reversal agents are freely available to all clinicians without restrictions. In this setting, we intended to evaluate how patient and surgical characteristics impacted the use of these agents for a variety of non-cardiac surgeries.