Intraperitoneal Injection of Graphene Oxide Nanoparticle Accelerates Stem Cell Therapy Effects on Acute Kidney Injury | Zendy

Tahereh Foroutan | Zendy; Mohsen Nafar | Zendy; Elaheh Motamedi | Zendy

Open Access

<p>Intraperitoneal Injection of Graphene Oxide Nanoparticle Accelerates Stem Cell Therapy Effects on Acute Kidney Injury</p>

Author(s) -

Tahereh Foroutan,

Mohsen Nafar,

Elaheh Motamedi

Publication year - 2020

Publication title -

stem cells and cloning advances and applications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.606

H-Index - 22

ISSN - 1178-6957

DOI - 10.2147/sccaa.s212087

Subject(s) - acute kidney injury , mesenchymal stem cell , creatinine , cisplatin , intraperitoneal injection , blood urea nitrogen , medicine , stem cell , stem cell therapy , kidney , necrosis , apoptosis , cancer research , pathology , chemotherapy , pharmacology , chemistry , biology , biochemistry , microbiology and biotechnology

Graphene-based nanostructures have shown some degree of stem cell protection against cell death. Acute kidney injury (AKI) is a major cause of mortality in hospitalized patients. Here, graphene oxide (GO) was used to improve the efficacy of bone marrow-derived mesenchymal stem cells (MSCs) in the treatment of AKI induced by cisplatin, a chemotherapy medication used to treat a number of cancers.

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