Open Access<p>Intraperitoneal Injection of Graphene Oxide Nanoparticle Accelerates Stem Cell Therapy Effects on Acute Kidney Injury</p>
Author(s) -
Tahereh Foroutan,
Mohsen Nafar,
Elaheh Motamedi
Publication year - 2020
Publication title -
stem cells and cloning
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 22
ISSN - 1178-6957
DOI - 10.2147/sccaa.s212087
Subject(s) - acute kidney injury , mesenchymal stem cell , creatinine , cisplatin , intraperitoneal injection , blood urea nitrogen , medicine , stem cell , stem cell therapy , kidney , necrosis , apoptosis , cancer research , pathology , chemotherapy , pharmacology , chemistry , biology , biochemistry , microbiology and biotechnology
Graphene-based nanostructures have shown some degree of stem cell protection against cell death. Acute kidney injury (AKI) is a major cause of mortality in hospitalized patients. Here, graphene oxide (GO) was used to improve the efficacy of bone marrow-derived mesenchymal stem cells (MSCs) in the treatment of AKI induced by cisplatin, a chemotherapy medication used to treat a number of cancers.