Open AccessApoptosis and G2/M arrest induced by Allium ursinum (ramson) watery extract in an AGS gastric cancer cell line
Author(s) -
Xiaoyan Xu,
Guo-Qing Song,
Yanqiu Yu,
MA Hai-ying,
Lifang Ma,
Yunan Jin
Publication year - 2013
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s45865
Subject(s) - apoptosis , cell cycle , cell cycle checkpoint , flow cytometry , cyclin b1 , blot , cyclin dependent kinase 1 , cell growth , cyclin , cell culture , chemistry , cell , microbiology and biotechnology , cancer research , biology , biochemistry , genetics , gene
The present study was designed to determine whether Allium ursinum L (ramson) could inhibit the proliferation of human AGS gastric cancer cells. Furthermore, we attempted to determine whether this inhibition could occur by targeting regulatory elements of the cell cycle.