Open AccessImpact of CHK2-small interfering RNA on CpG ODN7909-enhanced radiosensitivity in lung cancer A549 cells
Author(s) -
Wei Chen,
Xiaoqun Liu,
Tiankui Qiao,
Shengtao Yuan
Publication year - 2012
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s38240
Subject(s) - radiosensitivity , apoptosis , a549 cell , cpg site , cell cycle , flow cytometry , small interfering rna , cancer research , microbiology and biotechnology , biology , chemistry , dna methylation , medicine , rna , gene expression , biochemistry , gene , radiation therapy
To investigate the impact of checkpoint kinase 2 (CHK2)-small interfering RNA (CHK2-siRNA) on the enhancement of radiosensitivity by CpG oligodeoxynucleotide (ODN) 7909 in lung cancer A549 cells.