Open AccessLong Non-Coding RNA TRG-AS1 Promoted Proliferation and Invasion of Lung Cancer Cells Through the miR-224-5p/SMAD4 Axis
Author(s) -
Mengyan Zhang,
Weiguo Zhu,
Mansour Haeryfar,
Sumei Jiang,
Xiang Jiang,
Wei Chen,
Jiancheng Li
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s297336
Subject(s) - gene knockdown , downregulation and upregulation , cell growth , cancer research , lung cancer , western blot , long non coding rna , competing endogenous rna , biology , microrna , rna , cell culture , gentamicin protection assay , microbiology and biotechnology , medicine , pathology , gene , biochemistry , genetics
The aim of this study was to investigate the role and mechanism of long non-coding RNA (lncRNA) TRG-AS1 in mediating the proliferation, invasion and migration of lung cancer cells as well lung tumor growth.