Open AccessLncRNA EWSAT1 Promotes Colorectal Cancer Progression Through Sponging miR-326 to Modulate FBXL20 Expression
Author(s) -
Jing Liu,
Shimei Huang,
Xin Liao,
Zhongsheng Chen,
Lianghe Li,
Lei Yu,
Wei Zhan,
Rui Juan Li
Publication year - 2021
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s272895
Subject(s) - gene knockdown , cancer research , colorectal cancer , in vivo , cell growth , metastasis , medicine , in vitro , downregulation and upregulation , cancer , biology , cell culture , gene , genetics
Ewing sarcoma-associated transcript 1 ( EWSAT1 ) has been reported to be a pivotal modulator in a series of cancers. However, the function of EWSAT1 in colorectal cancer (CRC) has not been elaborated. This study aimed to explore the role of EWSAT1 in CRC progression and the underlying mechanisms.