Open Access<p>The LINC01260 Functions as a Tumor Suppressor via the miR-562/CYLD/NF-κB Pathway in Non-Small Cell Lung Cancer</p>
Author(s) -
Yangming Chen,
Yonghong Lei,
Jianbin Lin,
Yunchao Huang,
JiGuang Zhang,
Kai Chen,
Shenghong Sun,
Xiaolan Lin
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s253730
Subject(s) - downregulation and upregulation , gene knockdown , cancer research , carcinogenesis , western blot , cell growth , lung cancer , apoptosis , reporter gene , biology , chemistry , cancer , gene expression , gene , medicine , oncology , genetics
Recently, long noncoding RNAs (lncRNAs) have been identified as novel and potential therapeutic targets in various cancer types. Nonetheless, the levels and biological effects of lncRNAs in non-small cell lung cancer (NSCLC) remain largely unknown. In this study, we aimed to identify the effects of lncRNA-LINC01260 throughout the progression of NSCLC and explore the underlying mechanism.