lncRNA LSINCT5 Regulates miR-20a-5p/XIAP to Inhibit the Growth and Metastasis of Osteosarcoma Cells | Zendy

Shian Liao | Zendy; Jian Guan | Zendy; Hao Mo | Zendy; Juliang He | Zendy; Xinli Zhan | Zendy

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<p>lncRNA LSINCT5 Regulates miR-20a-5p/XIAP to Inhibit the Growth and Metastasis of Osteosarcoma Cells</p>

Author(s) -

Shian Liao,

Jian Guan,

Hao Mo,

Juliang He,

Xinli Zhan

Publication year - 2020

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s251843

Subject(s) - xiap , osteosarcoma , microrna , cancer research , metastasis , cell growth , oncogene , chemistry , rna , microbiology and biotechnology , biology , cell , gene , cell cycle , cancer , apoptosis , biochemistry , genetics , programmed cell death , caspase

More and more evidence has shown that non-coding RNA (ncRNA), including long ncRNA (lncRNA) and micro RNA (miRNA), plays a crucial regulatory role in osteosarcoma (OS). Previously, we revealed a Rho-related coiled coil incorporating protein kinase 1(XIAP). A transfer-related gene is negatively regulated by microRNA-20a-5p (miR-20a-5p) and plays the role of oncogene in OS. It is not clear if any lncRNA is involved in the axial upstream of miR-20a-5p/XIAP.

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