miR-30d Induced Apoptosis by Targeting Sox4 to Inhibit the Proliferation, Invasion and Migration of Nephroblastoma | Zendy

Shi Zong | Zendy; Jia Zhao | Zendy; Ling Liu | Zendy

Open Access

<p>miR-30d Induced Apoptosis by Targeting Sox4 to Inhibit the Proliferation, Invasion and Migration of Nephroblastoma</p>

Author(s) -

Shi Zong,

Jia Zhao,

Ling Liu

Publication year - 2020

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s251714

Subject(s) - apoptosis , microrna , sox4 , flow cytometry , cancer research , western blot , cell growth , cell culture , biology , microbiology and biotechnology , gene expression , gene , promoter , genetics

Wilms tumor (WT) is an embryonic malignant tumor, and its related mechanism is still unclear. microRNA (miR), as a short-chain non-coding RNA, has low expression in various tumors. In this study, WT differential miR was screened by multi-chip in GEO database and its mechanism was explored to provide potential therapeutic targets and ideas for clinic.

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