Open Access<p>miR-30d Induced Apoptosis by Targeting Sox4 to Inhibit the Proliferation, Invasion and Migration of Nephroblastoma</p>
Author(s) -
Shi Zong,
Jia Zhao,
Ling Liu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s251714
Subject(s) - apoptosis , microrna , sox4 , flow cytometry , cancer research , western blot , cell growth , cell culture , biology , microbiology and biotechnology , gene expression , gene , promoter , genetics
Wilms tumor (WT) is an embryonic malignant tumor, and its related mechanism is still unclear. microRNA (miR), as a short-chain non-coding RNA, has low expression in various tumors. In this study, WT differential miR was screened by multi-chip in GEO database and its mechanism was explored to provide potential therapeutic targets and ideas for clinic.