Open Access<p>MicroRNA-939 Directly Targets <em>HDGF</em> to Inhibit the Aggressiveness of Prostate Cancer via Deactivation of the WNT/β-Catenin Pathway</p>
Author(s) -
Jie Song,
Hao Zhang,
Jian Zi,
Ké Li,
Yunfei Mao,
Wentao Huang
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s250101
Subject(s) - gene silencing , downregulation and upregulation , cancer research , microrna , cell growth , carcinogenesis , wnt signaling pathway , biology , prostate cancer , cancer , chemistry , microbiology and biotechnology , signal transduction , gene , biochemistry , genetics
MicroRNA-939 (miR-939) has crucial roles in several types of human cancer. However, the expression profile and precise functions of miR-939 in prostate cancer (PCa) are still unclear. This study aimed to determine miR-939 expression in PCa and explore its roles in PCa tumorigenesis.