Open Access<p>miR-96-5p Suppresses the Progression of Nasopharyngeal Carcinoma by Targeting CDK1</p>
Author(s) -
Xiaoqin Luo,
Xian He,
Xing Liu,
Lunkun Zhong,
Wenjian Hu
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s248338
Subject(s) - nasopharyngeal carcinoma , cyclin dependent kinase 1 , apoptosis , cancer research , cell cycle , flow cytometry , in vivo , viability assay , survivin , chemistry , biology , medicine , microbiology and biotechnology , radiation therapy , biochemistry
Nasopharyngeal carcinoma (NPC) is a malignant tumor that occurs in the nasopharyngeal mucosa. Clinically, radiotherapy is the preferred treatment for NPC, and cervical lymph node metastasis is easy to emerge in the early stage. Therefore, this study aimed to investigate the role and potential molecular mechanisms of miR-96-5p in NPC cells to develop new therapeutic horizons.