CCDC7 Activates Interleukin-6 and Vascular Endothelial Growth Factor to Promote Proliferation via the JAK-STAT3 Pathway in Cervical Cancer Cells | Zendy

Cong Zhou | Zendy; Xianghuo He | Zendy; Qi Zeng | Zendy; Peng Zhang | Zendy; Chunting Wang | Zendy

Open Access

<p>CCDC7 Activates Interleukin-6 and Vascular Endothelial Growth Factor to Promote Proliferation via the JAK-STAT3 Pathway in Cervical Cancer Cells</p>

Author(s) -

Cong Zhou,

Xianghuo He,

Qi Zeng,

Peng Zhang,

Chunting Wang

Publication year - 2020

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s244663

Subject(s) - stat3 , cancer research , vascular endothelial growth factor , medicine , vascular endothelial growth factor c , interleukin 6 , growth factor , signal transduction , vascular endothelial growth factor a , immunology , cytokine , vegf receptors , microbiology and biotechnology , biology , receptor

Tumor growth is one of the most lethal attributes of human malignancy. The expression of CCDC7, a novel gene which has multiple functions, has been shown to be associated with tumor growth and poor prognosis in patients with cancer. However, the specific functions of CCDC7 remain unclear. Here, we investigated the molecular mechanisms underlying the effects of CCDC7 on proliferation in cervical cancer.

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