Open Access<p>Meg3 Induces EMT and Invasion of Glioma Cells via Autophagy</p>
Author(s) -
Zhihao Yang,
Erbao Bian,
Yadi Xu,
Xinghu Ji,
Feng Tian,
Chunchun Ma,
Hongliang Wang,
Bing Zhao
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s239648
Subject(s) - meg3 , glioma , autophagy , cancer research , long non coding rna , malat1 , blot , cell migration , medicine , biology , pathology , cell , gene , rna , apoptosis , genetics
Glioma is one of the most common malignant tumors. Glioblastoma (grade IV) is considered the most malignant form of human brain tumors. Maternal expression gene 3 (Meg3) encodes a non-coding RNA (ncRNA) that plays an important role in the development and progression of cancer. However, the role of Meg3 in glioma cells remains largely unclear.