UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1 | Zendy

Tian-rong Xing | Zendy; Ping Chen | Zendy; Jiamei Wu | Zendy; Lili Gao | Zendy; Wei Yang | Zendy; Yu Cheng | Zendy; Li-bo Tong | Zendy

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<p>UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1</p>

Author(s) -

Tian-rong Xing,

Ping Chen,

Jiamei Wu,

Lili Gao,

Wei Yang,

Yu Cheng,

Li-bo Tong

Publication year - 2020

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s233149

Subject(s) - pvt1 , chemistry , microbiology and biotechnology , rna , immunoprecipitation , cancer research , long non coding rna , gene , biology , biochemistry

Endometrial carcinoma (EC) is the primary cause of death associated with cancer globally. Thus, the possible molecular mechanism of EC needs further exploration. Up-frameshift protein 1 ( UPF1 ) is an ATPase depending on RNA/DNA and RNA helicase depending on ATP. Long noncoding RNA (lncRNA) plasmacytoma variant translocation 1 ( PVT1 ) was dysregulated in diverse diseases.

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