Open Access<p>UPF1 Participates in the Progression of Endometrial Cancer by Inhibiting the Expression of lncRNA PVT1</p>
Author(s) -
Tian-Rong Xing,
Ping Chen,
Jia-Mei Wu,
Lili Gao,
Wei Yang,
Yu Cheng,
Tong Li-bo
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s233149
Subject(s) - pvt1 , chemistry , microbiology and biotechnology , rna , immunoprecipitation , cancer research , long non coding rna , gene , biology , biochemistry
Endometrial carcinoma (EC) is the primary cause of death associated with cancer globally. Thus, the possible molecular mechanism of EC needs further exploration. Up-frameshift protein 1 ( UPF1 ) is an ATPase depending on RNA/DNA and RNA helicase depending on ATP. Long noncoding RNA (lncRNA) plasmacytoma variant translocation 1 ( PVT1 ) was dysregulated in diverse diseases.