Open Access<p>The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis</p>
Author(s) -
Yilun Shang,
Qinghai Wang,
Jian Li,
Qiangqiang Zhao,
Xueyuan Huang,
Hang Dong,
Haiting Liu,
Ye Zhang,
Junhua Zhang,
Rong Gui,
Xinmin Nie
Publication year - 2020
Publication title -
oncotargets and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.054
H-Index - 60
ISSN - 1178-6930
DOI - 10.2147/ott.s232594
Subject(s) - apoptosis , downregulation and upregulation , microbiology and biotechnology , tunel assay , chemistry , cell cycle , viability assay , cell cycle checkpoint , biology , biochemistry , gene
Isatin derivatives have extensive biological activities, such as antitumor. IF203, a novel isatin derivative, has not previously been reported to have antitumor activity.