MicroRNA-769-5p Inhibits Pancreatic Ductal Adenocarcinoma Progression by Directly Targeting and Downregulating ETS Proto-Oncogene 1 | Zendy

Kai Cheng | Zendy; Feng Lan | Zendy; Yu Shuang | Zendy; Changhong Yu | Zendy; Nannan Chi | Zendy

Open Access

<p>MicroRNA-769-5p Inhibits Pancreatic Ductal Adenocarcinoma Progression by Directly Targeting and Downregulating ETS Proto-Oncogene 1</p>

Author(s) -

Kai Cheng,

Feng Lan,

Yu Shuang,

Changhong Yu,

Nannan Chi

Publication year - 2020

Publication title -

oncotargets and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.054

H-Index - 60

ISSN - 1178-6930

DOI - 10.2147/ott.s218876

Subject(s) - pancreatic ductal adenocarcinoma , microrna , oncogene , cancer research , medicine , oncology , bioinformatics , biology , pancreatic cancer , cancer , gene , genetics , cell cycle

MicroRNA-769-5p (miR-769) is aberrantly expressed and plays crucial roles in non-small cell lung cancer and melanoma. However, the expression pattern, biological role, and mechanisms of action of miR-769 in pancreatic ductal adenocarcinoma (PDAC) are yet to be fully elucidated. Therefore, we attempted to determine the potential regulatory function of miR-769 in PDAC progression and to explore the underlying mechanisms in detail.

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