H-2g, a glucose analog of blood group H antigen, mediates monocyte recruitment in vitro and in vivo via IL-8/CXCL8 | Zendy

Bradley J. Rabquer | Zendy; Yong Hou | Zendy; Jeffrey H. Ruth | Zendy; Wei Luo | Zendy; Eitzman | Zendy; Alisa E. Koch | Zendy; Asif Amin | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

H-2g, a glucose analog of blood group H antigen, mediates monocyte recruitment in vitro and in vivo via IL-8/CXCL8

Author(s) -

Bradley J. Rabquer,

Yong Hou,

Jeffrey H. Ruth,

Wei Luo,

Eitzman,

Alisa E. Koch,

Asif Amin

Publication year - 2012

Publication title -

open access rheumatology research and reviews

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.63

H-Index - 14

ISSN - 1179-156X

DOI - 10.2147/oarrr.s36163

Subject(s) - in vivo , in vitro , monocyte , interleukin 8 , microbiology and biotechnology , chemistry , antigen , immunology , biology , inflammation , biochemistry , genetics

Monocyte (MN) recruitment is an essential inflammatory component of many autoimmune diseases, including rheumatoid arthritis (RA). In this study we investigated the ability of 2-fucosyllactose (H-2g), a glucose analog of blood group H antigen to induce MN migration in vivo and determined if H-2g-induced interleukin-8 (IL-8/CXCL8) plays a role in MN ingress in RA.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research