Open AccessSevere Intermittent Hypoxia Modulates the Macrophage Phenotype and Impairs Wound Healing Through Downregulation of HIF-2α
Author(s) -
Lihong Chen,
Yunyi Gao,
Yan Li,
Chun Wang,
Fan Chen,
Yun Gao,
Xingwu Ran
Publication year - 2022
Publication title -
nature and science of sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.715
H-Index - 34
ISSN - 1179-1608
DOI - 10.2147/nss.s382275
Subject(s) - intermittent hypoxia , hypoxia (environmental) , wound healing , medicine , hacat , downregulation and upregulation , macrophage polarization , inflammation , proinflammatory cytokine , m2 macrophage , immunology , in vitro , pathology , macrophage , obstructive sleep apnea , biology , chemistry , biochemistry , organic chemistry , oxygen , gene