Open AccessThe 3% Oxygen Desaturation Index is an Independent Risk Factor for Hypertension Among Children with Obstructive Sleep Apnea
Author(s) -
HaiHua Chuang,
Chao-Yung Wang,
LiPang Chuang,
YuShu Huang,
HsuehYu Li,
TuanJen Fang,
Rong-Ho Lin,
LiAng Lee
Publication year - 2022
Publication title -
nature and science of sleep
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.715
H-Index - 34
ISSN - 1179-1608
DOI - 10.2147/nss.s362557
Subject(s) - medicine , obstructive sleep apnea , odds ratio , body mass index , polysomnography , overweight , risk factor , hypoxemia , obesity , confidence interval , sleep apnea , logistic regression , apnea , pediatrics
Obstructive sleep apnea (OSA) and obesity are both directional risk factors of hypertension. Chronic intermittent hypoxemia (IH) is a commonly observed pathophysiological mechanism involved in multiple comorbidities of OSA. However, their interactions are not well understood in children. This study aimed to investigate the associations of IH indexes (oxygen desaturation index 3% [ODI3], mean peripheral oxygen saturation [SpO 2 ], least SpO 2 , and time with SpO 2 < 85%), apnea-hypopnea index, and weight status with hypertension in a sample of pediatric OSA patients.