Open Access<p>Characterising Vascular Cell Monolayers Using Electrochemical Impedance Spectroscopy and a Novel Electroanalytical Plot</p>
Author(s) -
Anubhav Bussooa
Publication year - 2020
Publication title -
nanotechnology, science and applications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.051
H-Index - 28
ISSN - 1177-8903
DOI - 10.2147/nsa.s266663
Subject(s) - nyquist plot , dielectric spectroscopy , monolayer , electrical impedance , analytical chemistry (journal) , cyclic voltammetry , bode plot , electrode , plot (graphics) , materials science , electrochemical cell , biomedical engineering , chemistry , nanotechnology , biological system , electrochemistry , electrical engineering , mathematics , engineering , chromatography , biology , statistics , transfer function
Biological research relies on the culture of mammalian cells, which are prone to changes in phenotype during experiments involving several passages of cells. In regenerative medicine, specifically, there is an increasing need to expand the characterisation landscape for stem cells by identifying novel stable markers. This paper reports on a novel electric cell-substrate impedance sensing-based electroanalytical diagram which can be used for the "electrical characterisation" of cell monolayers consisting of smooth muscle cells, endothelial cells or co-culture.