Transcription Factor E2F1 Aggravates Neurological Injury in Ischemic Stroke via microRNA-122-Targeted Sprouty2 | Zendy

Yunxia Wu | Zendy; Zhiqiang Gao | Zendy; Jiang Zhang | Zendy

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<p>Transcription Factor E2F1 Aggravates Neurological Injury in Ischemic Stroke via microRNA-122-Targeted Sprouty2</p>

Author(s) -

Yunxia Wu,

Zhiqiang Gao,

Jiang Zhang

Publication year - 2020

Publication title -

neuropsychiatric disease and treatment

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 0.819

H-Index - 67

eISSN - 1178-2021

pISSN - 1176-6328

DOI - 10.2147/ndt.s271320

Subject(s) - e2f1 , apoptosis , medicine , microrna , autophagy , cell cycle , cancer research , viability assay , transcription factor , mapk/erk pathway , microbiology and biotechnology , biology , signal transduction , cancer , biochemistry , gene

It has been documented that microRNAs (miRs) assume a pivotal role in the development of ischemic stroke (IS). However, it remains poorly identified about the role of miR-122 in IS. Herein, this study was intended to explore the mechanism of E2F1-orchestrated miR-122 in IS.

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