Open Access<p>Mu-Opioid Receptor Polymorphism Moderates Sensitivity to Parental Behaviors During Characterization of Personality Traits</p>
Author(s) -
Keisuke Noto,
Akihito Suzuki,
Toshinori Shirata,
Yoshihiko Matsumoto,
Nana Takahashi,
Kaoru Goto,
Koichi Otani
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s265774
Subject(s) - cooperativeness , temperament and character inventory , temperament , personality , medicine , genotype , big five personality traits , clinical psychology , opioid receptor , opioid , reward dependence , polymorphism (computer science) , receptor , harm avoidance , gene , genetics , psychology , biology , social psychology
Attachment research shows that attachment experiences with parents in childhood influence the characterization of personality traits. Meanwhile, it is known that mu-opioid receptor function is involved in human attachment. Furthermore, a few studies suggest that the A118G polymorphism of the mu-opioid receptor gene ( OPRM1 ) is associated with altered mu-opioid receptor function. Thus, we examined if the OPRM1 polymorphism moderates the sensitivity to parental behaviors and thereby contributes to the characterization of personality traits.