Open Access<p>Frontocingulate Dysfunction Is Associated with Depression and Decreased Serum PON1 in Methamphetamine-Dependent Patients</p>
Author(s) -
Nooshin Ghavidel,
Fariba Khodagholi,
Abolhassan Ahmadiani,
Reza Khosrowabadi,
Sareh Asadi,
Jamal Shams
Publication year - 2020
Publication title -
neuropsychiatric disease and treatment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.819
H-Index - 67
eISSN - 1178-2021
pISSN - 1176-6328
DOI - 10.2147/ndt.s237528
Subject(s) - stroop effect , medicine , anterior cingulate cortex , anxiety , depression (economics) , methamphetamine , mood , audiology , psychiatry , clinical psychology , cognition , economics , macroeconomics
Studies have been reported that frequent use of methamphetamine (MA) is associated with brain function impairment, mood disorders and excessive free radical production accompanied by the decreased level of the antioxidant response elements, but no study investigated their correlations simultaneously. In the current study, the correlation of brain function, depression and anxiety levels, and the serum levels of PON1 (an antioxidant) in MA-dependent patients were investigated.