Open Access<p>Anesthesia Options and the Recurrence of Cancer: What We Know so Far?</p>
Author(s) -
Juan P. Cata,
Carlos Guerra,
Germán Soto,
María F. Ramirez
Publication year - 2020
Publication title -
local and regional anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.679
H-Index - 17
ISSN - 1178-7112
DOI - 10.2147/lra.s240567
Subject(s) - medicine , cancer surgery , cancer , metastasis , anesthesia , narrative review , distant metastasis , regional anesthesia , surgery , intensive care medicine
Surgery is a critical period in the survival of patients with cancer. While resective surgery of primary tumors has shown to prolong the life of these patients, it can also promote mechanisms associated with metastatic progression. During surgery, patients require general and sometimes local anesthetics that also modulate mechanisms that can favor or reduce metastasis. In this narrative review, we summarized the evidence about the impact of local, regional and general anesthesia on metastatic mechanisms and the survival of patients. The available evidence suggests that cancer recurrence is not significantly impacted by neither regional anesthesia nor volatile or total intravenous anesthesia.