Open AccessIn situ Injection of pH- and Temperature-Sensitive Nanomaterials Increases Chemo-Photothermal Efficacy by Alleviating the Tumor Immunosuppressive Microenvironment
Author(s) -
Jianhua Liu,
Liantao Guo,
Rong Yan,
Weijie Zheng,
Dongcheng Gao,
Jing Zhang,
Lan Luo,
Xinwen Kuang,
Saraswati Sukumar,
Yi Tu,
Chuang Chen,
Shengrong Sun
Publication year - 2022
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s367121
Subject(s) - photothermal therapy , tumor microenvironment , nanomaterials , in situ , materials science , cancer research , nanotechnology , biophysics , chemistry , medicine , tumor cells , biology , organic chemistry
Triple-negative breast cancer (TNBC) is challenging to treat with traditional "standard of care" therapy due to the lack of targetable biomarkers and rapid progression to distant metastasis.