Open AccessInhibition of Circulating Exosomal miRNA-20b-5p Accelerates Diabetic Wound Repair
Author(s) -
Kai Chen,
Tao Yu,
Xin Wang
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s287875
Subject(s) - microvesicles , wound healing , microrna , exosome , in vivo , vascular endothelial growth factor a , medicine , vascular endothelial growth factor , cancer research , microbiology and biotechnology , immunology , biology , vegf receptors , gene , biochemistry
Efficient approaches to reliably improving wound healing in diabetic patients remain to be developed. Exosomes are nanomaterials from which therapeutically active microRNAs (miRNAs) can be isolated. In the present report, we therefore isolated circulating exosome-derived miRNAs from patients with diabetes and assessed the impact of these molecules on wound healing.