Open Access<p>Formulation of Aceclofenac Tablets Using Nanosuspension as Granulating Agent: An Attempt to Enhance Dissolution Rate and Oral Bioavailability</p>
Author(s) -
Haroon Rahim,
Abdul Sadiq,
Riaz Ullah,
Ahmed Bari,
Fazli Amin,
Umar Farooq,
Naeem Ullah Jan,
Hafiz Majid Mahmood
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s270746
Subject(s) - aceclofenac , bioavailability , particle size , friability , materials science , angle of repose , dissolution , chromatography , cmax , sonication , nuclear chemistry , chemistry , pharmacology , first pass effect , medicine , organic chemistry , composite material
The aim of the studies was to fabricate aceclofenac (AC) tablets using nanosuspension as granulating fluid to boost its rate of in vitro dissolution and eventually its oral bioavailability.