Open AccessProfile of Bacteria with ARGs Among Real-World Samples from ICU Admission Patients with Pulmonary Infection Revealed by Metagenomic NGS
Author(s) -
Huijuan Chen,
Xinhua Bai,
Yang Gao,
Liu Wen-xuan,
Xuena Yao,
Jing Wang
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s335864
Subject(s) - enterococcus faecium , bacteria , microbiology and biotechnology , antibiotic resistance , antibiotics , acinetobacter baumannii , sputum , drug resistance , biology , enterococcus , medicine , tuberculosis , pseudomonas aeruginosa , pathology , genetics
Treatment of pulmonary infections in the intensive care unit (ICU) represents a great challenge, especially infections caused by antibiotic resistance pathogens. A thorough and up-to-date knowledge of the local spectrum of antibiotic resistant bacteria can improve the antibiotic treatment efficiency. In this study, we aimed to reveal the profile of bacteria with antibiotic resistance genes (ARGs) in real-world samples from ICU admission patients with pulmonary infection in Mainland, China, by metagenomic next-generation sequencing (mNGS).